窒息新生儿血糖监测的临床意义

Clinical Significance of Blood Glucose Measurements in Neonates with Birth Asphyxia

目的:探讨不同程度窒息新生儿的血糖变化及临床意义。方法:我院新生儿科收治的窒息新生儿108例,均于入院后采集足跟外周静脉血进行微量血糖监测,监测频度每天8～10次,记录血糖值,分析窒息程度与血糖值之间的关系。结果:入院48 h内,轻度窒息组血糖异常率为35.96%,重度窒息组血糖异常率为94.74%,两组比较差异有统计学意义(P<0.01)。48 h后经治疗轻度窒息组血糖异常率为4.49%,重度窒息组血糖异常率为21.05%,两组比较差异有有统计学意义(P<0.05)。轻度窒息新生儿血糖异常以低血糖为主,重度窒息新生儿血糖异常以高血糖为主。结论:窒息新生儿要密切观察血糖动态变化,特别是重度窒息患儿,应将血糖监测结果作为判断病情及预后的辅助指标。

Objective： To investigate the changes and clinical significance of blood glucose levels in neonates with birth asphyxia.Methods： One hundred and eight neonates with birth asphyxia was included,collecting the heel peripheral blood to monitore traces of blood glucose 8~10 times daily and analysing the relationship between the apnea and blood glucose level.Result： Within 48 hours＇ hospitalization,the abnormal rate of blood glucose in the mild asphyxia group was 35.96%,while the severe asphyxia group was 94.74%,the difference was significent（P0.01）.48 hours after trentment,the abnormal rate of blood glucose in the mild asphyxia group was 4.49%,while the severe asphyxia group was 21.05%,the difference was significent（P0.05）.Children with mild neonatal asphyxia mainly had hypoglycemia,while children with severe neonatal asphyxia mainly had hyperglycemia.Conclusions： We should monitor the change of blood glucose closely especially severe asphyxia.The changes of blood glucose should be used as an index for disease diagnosis and prognosis.