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抗癫痫药物对儿童生长发育的影响 被引量：6

Effect of Anti-Epileptic Drugs on Growth and Development of Children
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摘要 癫痫是神经内科一种常见慢性疾病,由许多不明病因引起脑部神经元高度同步化而异常放电所致的中枢神经系统功能失常综合征,全球约5千万人受该病的影响,目前以药物治疗为主,通过药物治疗约50%的患者能够治愈,另外25%的患者症状能够缓解[1]。
作者 黄彦臻 黄志
机构地区 重庆医科大学附属儿童医院
出处 《儿科药学杂志》 CAS 2013年第7期57-60,共4页 Journal of Pediatric Pharmacy
关键词 抗癫痫药物 儿童生长发育 中枢神经系统 慢性疾病 神经内科 功能失常 异常放电 药物治疗
分类号 R742.1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献35

  • 1Goldenberg MM. Overview of drugs used for epilepsy and seizures : etiology, diagnosis, and treatment [ J ]. Pharmacy and Therapeutics, 2010, 35 (7) : 392-415.
  • 2Guerrini R, Zaccara G, La Marca G, et al. Safety and Tolerability of Antiepileptic Drug Treatment in Children with Epilepsy [ J ]. Drug Safety, 2012, 35(7) : 519-533.
  • 3Kwong KL, Tsui KW, Wu SP, et al. Utilization of Antiepileptic Drugs in Hong Kong Children [J]. Pediatric neurology, 2012, 46(5) :281-286.
  • 4Cansu A, Yesilkaya E, Serdaroglu A, et al. The Effects of Oxcarbazepine and Valproate Therapies on Growth in Children with Epilepsy [J]. Endocrine Research, 2012, 37(4), 163-174.
  • 5许莉,张金环,许前.拉莫三嗪、卡马西平及丙戊酸对癫痫患儿的骨质影响[J].中国实用医药,2011,6(11):166-167. 被引量：6
  • 6Borusiak P, Langer T, Heruth M, et al. Antiepileptic Drugs and Bone Metabolism in Children: Data from 128 Patients [ J ]. Journal of Child Neurology, 2012, 28( 1 ) : 1-8.
  • 7Aygun F, Ekici B, Aydiinlii N, et al. Thyroid Hormones in Children on Antiepileptic Therapy [ J ]. International Journal of Neuroscience, 2012, 122(2): 69-73.
  • 8Alberto Verrotti, Melissa Laus, Alessandra Scardapane, et al. Thyroid hormones in children with epilepsy during long-term administration of carbamazepine and valproate [ J ]. European Journal of Endocrinology, 2009, 160 : 81-86.
  • 9Antel J, Hebebrand J. Weight-Reducing Side Effects of the Antiepileptic Agents Topiramate and Zonisamide [ J]. Handb EXP pharmcol, 2012, (209) : 433-466.
  • 10Kanemura H, Sano F, Maeda Y, et al. Valproate sodium enhances body weight gain in patients with childhood epilepsy: a pathogenic mechanisms and open-label clinical trial of behavior therapy [J]. Seizure, 2012, 21(7): 496-500.

二级参考文献26

  • 1朱海霞,蔡方成,张晓萍.长程服用苯巴比妥、氯硝安定、丙戊酸和托吡酯对未成熟脑发育影响的实验研究[J].中华儿科杂志,2007,45(2):121-125. 被引量：16
  • 2Arcas J, Ferrer T, Roche MC, et al. Hypohidrosis related to the administration of topiramate to children. Epilepsia, 2001, 42(10): 1363.
  • 3Carolis P, Magnifico F, Pierangeli G, et al. Transient hypohidrosis induced by topiramate. Epilepsia, 2003, 44(7): 974.
  • 4Ben-Zeev B, Watemberg N, Augarten A, et al. Oligohydrosis and hyperthermia: pilot study of a novel topiramate adverse effect. J Child Neurol,2003, 18(4): 254.
  • 5Bono A, Beghi E, Bogliun G, et aL Antiepileptic drugs and peripheral nerve function: a multicenter screening investigation of 141 patients with chronic treatment. Epilepsia, 1993, 34:323- 331.
  • 6Wang Y, Zhou D, Wang B, et aL A kindling model of pharmacoresistant temporal lobe epilepsy in Sprague-Dawley rats induced by Coriaria lactone and its possible mechanism. Epilepsia, 2003, 44:475-488.
  • 7Xiang SL, Zhong M, Cai FC, et aL The sialic acid residue is a crucial component of C. jejuni lipooligosaccharide ganglioside mimicry in the induction Guillain-Barre syndrome. J Neuroimmunol, 2006, 174 : 126-132.
  • 8Vincent AM, Russell JW, Low P, et aL Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr Rev, 2004, 25:612- 628.
  • 9Aycicek A, Iscan A. The effects of carbamazepine, valproic acid and phenobarbital on the oxidative and antioxidative balance in epileptic children. Eur Neural, 2007, 57(2) :65-69.
  • 10Michoulas A, Tong V, Teng XW, et al. Oxidative stress in children receiving valproic acid. J Pediatr, 2006, 149:692-696.

共引文献11

同被引文献37

  • 1邵湘宁.刘氏小儿推拿取穴特点刍议[J].湖南中医杂志,2005,21(5):54-54. 被引量：27
  • 2邓星强,李瑞,梁丽君,沈桂芳,祁佰祥,安琪.托吡酯治疗小儿癫痫临床观察[J].中国医院药学杂志,2006,26(3):322-323. 被引量：9
  • 3王华.小儿抗癫痫药物的合理应用[J].儿科药学杂志,2007,13(6):1-4. 被引量：7
  • 4Lee JW,Dworetzky B. Rational Polytherapy with Antiepileptic Drugs[J].{H}PHARMACEUTICALS,2010,(8):2362-2379.
  • 5Privitera MD, Brodie M J, Mattson RH, et d.Topiramate, car- bamazepine and valproate monotherapy:double-blind com- parison in newly diagnosed epilepsy [J].Acta Neurol Scand, 2003,107(3) : 165-175.
  • 6Marson AG, AI-Khanmsi AM,Alwaidh M,et a/.The SANAD study of effectiveness of valpreate, lamotrigine, or topiramate for generalized and unclassifiable epilepsy:an ubblinded randomized controlled trial[J].Lancet, 2007,369 (9566) : 1016-1026.
  • 7Himmerich H,Bartsch S,Hamer H,et a/.Impact of mood stabilizers and antiepileptic drugs on cytokine production in-vitro[J].Psychiatr Res, 2013,47( 11 ) : 1751-1759.
  • 8Lynch BA, Lambeng N, Nocka K, et a/.The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam[J].Proc Natl Acad Sci USA, 2004,101 (26) : 9861-9866.
  • 9Glauser T, Ben -Menachem E, Bourgeois B,et a/.Updated ILAE evidence review of a ntiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes[J].Epilepsia, 2013,54(3) : 551-563.
  • 10权青云,赵静霞.抗癫痫药物及其对认知功能影响的研究进展[J].国际神经病学神经外科学杂志,2009,36(1):69-72. 被引量：16

引证文献6

二级引证文献29

儿科药学杂志
2013年 第7期

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