急性冠脉综合征患者内皮祖细胞及C反应蛋白的变化

Analysis and control measures of multi-resistant bacteria of Pediatric intensive care unit patients

目的分析急性冠脉综合征患者的内皮祖细胞(即EPCs)以及C-反应蛋白(即hsCRP)的变化。方法收集急性冠脉综合征患者42例,其中23例急性心肌梗死(A组),19例不稳定型心绞痛(B组),并选择同期行冠脉造影并排除冠心病的正常人20例作为对照组,两组均进行EPCs计数以及hsCRP浓度检测。结果 A组和B组外周血中的EPCs数量以及hsCRP浓度显著高于对照组,且A组均显著高于B组;EPCs数量与hsCRP浓度呈显著正相关,P<0.05。结论急性冠脉综合征患者血中的EPCs数量以及hsCRP浓度均显著增加,主要是由于炎症因子激活骨髓干细胞,并使其分化成为EPCs后参与血管修复所致。

Objective Analysis of patients with acute coronary syndrome endothelial progenitor cells （EPCs） and C reactive protein （hsCRP） changes. Mefllods To collect 42 cases of patients with acute coronary syndrome is comprehensive, including 23 cases of acute myocardial infarction （A group）, 19 patients with unstable angina pectoris （B group）, and underwent coronary angiography and the exclusion of coronary heart disease in 20 normal subjects as control group, two groups were EPCs count and hsCRP concentration detection. Results In group A and group B EPCs in the peripheral blood and the concentration of hsCRP was significantly higher than that in control group, and A group were significantly higher than those in group B; the number of EPCs was significantly correlated with the concentration of hsCRP, P〈0.05. Conclusion The patients with acute coronary syndrome of blood EPCs and hsCRP concentration increased significantly, mainly due to inflammatory cytokines activated bone marrow stem cells, which differentiate into EPCs in the vascular repair caused by.