呼吸内科病房院内肺部真菌感染研究

Study on respiratory nosocomial pulmonary fungal infection in Department of Internal Medicine

目的探讨呼吸内科病房院内肺部真茵感染危险因素、真茵类型及治疗现状。方法对2011年3月—2012年8月该院呼吸内科收治的104例病房院内肺部真菌感染患者资料进行回顾性分析。结果主要病原菌是酵母菌属71例(68.2%),其中白色假丝酵母菌最多(42例,59.1%),光滑假丝酵母菌(18例,25.3%),其它酵母菌(11例,15.4%)。其次为曲霉菌属32例(30.7%)。白色念珠菌最多,慢性阻塞性肺疾病最为多见。合并有糖尿病等基础性疾病的继发感染是肺部真茵感染的重要原因,长期机械通气,长期使用激素及广谱抗生素是其主要诱因。结论对于院内肺部真菌感染,早诊断,早发现早治疗,减少易感因素是关键。

Objective To investigate the risk factors of respiratory ward, Department of internal medicine nosocomial pulmonary fungus infection fungi types and treatment status. Methods A retrospective analysis was performed in 104 cases with pulmonary fungal infection in wards from March to 2012 to 2011 August in our hospital were treated in the Department of internal medicine. Results The major pathogenic bacteria yeast genera and 71 cases （68.2%）, wherein the Candida albicans most （42 cases, 59.1%）, Candida glabrata （18 cases, 25.3%）, other yeasts （ 11 cases, 15.4%）.Followed by Aspergillus species in 32 cases （30.7%）. Candida albicans, chronic obstructive pulmonary disease is the most common. The patients with diabetes and other diseases of secondary infection is an important cause of pulmonary fungus infection, long-term mechanical ventilation, long-term use of hormones and antibiotics is the main inducement. Conclusion The pulmonary fungal infection in hospital, early diagnosis, early detection and early treatment, reduce the susceptible factors is the key.