炎敌油用于希罗达治疗乳腺癌所致手足综合征的疗效观察

Clinical efficacy of Yan-Di-Oil on hand-foot syndrome induced by xeloda treating breast cancer

目的观察炎敌油用于希罗达(卡培他滨)治疗乳腺癌所致手足综合征的临床疗效。方法采用病例对照研究的方法,选择53例乳腺癌口服希罗达患者,随机分为实验组29例和对照组24例。对照组口服希罗达同时给予常规护理及口服维生素B6,实验组在常规护理的基础上同时涂抹炎敌油。观察两组手足综合征的发生情况。结果实验组手足综合征的发生率为34.5%,对照组为58.3%,两组比较差异有统计学意义(P<0.05)。结论炎敌油对防治口服希罗达所致手足综合征有一定的疗效。

Objective To observe the clinical efficacy of Yan-Di-Oil on hand-foot syndrome caused by xeloda（capecitabine tablets）treating breast cancer.Methods 53 patients with breast cancer treated by xeloda were randomly divided into treatment group（n=29）and control group（n=24）.Patients in control group took xeloda and routine nursing and vitamin B6,treatment group was given Yan-Di-Oil on the basis of the routine nuring.The occurrence of hand-foot syndrome of both groups was observed.Results The incidence rates of hand-foot syndrome of treatment group and control sroup were 34.5% and 58.3% respectively,there was significant difference between the two groups（P0.05）.Conclusion Yan-Di-Oil has certain curative effect on hand-foot syndrome caused by taking xeloda orally.