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生脉汤对大鼠非特异性免疫功能的影响 被引量:4

The Effect Of Shengmai Tang On Rat immune function
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摘要 目的:观察生脉汤对大鼠非特异性免疫功能的影响。方法:将大鼠随机分为正常对照组、模型组、西药对照组(转移因子)、生脉汤低、中、高剂量组,分别于第1、11、21天,腹腔注射环磷酰胺造成免疫低下模型。于第30天,称重,取胸腺和脾脏,计算脏器指数。结果:与模型组比较,各中药组均可使上述指标显著增加(P<0.01),生脉汤中剂量组的作用强于西药组(P<0.05)。结论:生脉汤能明显增加免疫低下大鼠脏器指数、NK细胞数量和TNF-α含量,对非特异性免疫功能有明显增强作用。 Objective : To study the effect of Sheng Maitang on rat nonspecific immunity. Methods : The rats were randomly divided into six groups:control group ,model group, control group of western medicine , high ,middle,low dose group of Shengmai Tang. Animmun osup- pressive animal model is established by cyelophosphamide(CY) on day1,21,30. On day 30,after taking Thymus gland ,spleen and blood , organ index ,quantity of NK cell and amount of TNF - α will be measured. Results : Every administration group of Sheng Maitang increases differently Comparing the model group(P 〈 0.01 ). The middle group is better by Comparison of control group of western medicine (P 〈 0. 05 ). Conclusion: Sheng Maitang can incease the organ index,quantity of NK cell and amount of TNF -α remarkably, and enhance the nonspeeific immunity in cyelophosphamide rats.
作者 郑丽莉
机构地区 山东协和学院
出处 《内蒙古中医药》 2013年第16期77-78,共2页 Inner Mongolia Journal of Traditional Chinese Medicine
关键词 生脉汤 脏器指数 TNF-Α NK细胞 Sheng Maitang organ index NK cell TNF - α
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