13例先兆子痫、子痫合并可逆性后部脑病综合征临床分析

Clinicol analysis on 13 patients PRES with precdampsia and eclampsia WANG Yun-ling SHAN Yin-chang JIN Lie Fengcheng Hospital of Shanghai city Fengxian Qu ,Shanghai 201411

目的:总结先兆子痫、子痫合并可逆性后部脑病综合征(RPES)的临床表现及影像学特点,提高对该病的认识。方法:回顾性分析13例先兆子痫、子痫合并RPES患者的临床和影像学资料。结果:头痛、癫痫发作、意识障碍、视力障碍是RPES常见四联征,影像学主要表现为大脑后部对称性白质水肿,CT低密度灶,T1WI上呈等信号或略低信号,T2WI及FLAIR上呈明显高信号。经过治疗,13例患者临床症状、影像学异常迅速恢复。结论:头痛、癫痫、意识障碍、视力障碍是RPES主要临床表现,血压急性升高是RPES的重要体征,影像学特征是大脑后部对称性白质水肿,而非梗死,大多数患者经治疗很快恢复。

Objective： To summarize the clinical and imaging characteristics of PRES with preeclampsia and eclampsia and to improve the recognition of this disease. Methods ：The clinical data of PRES in 13 patients with preeclampsia and eclampsia were analyzed retrospec- tively. Results ：The common tetrad are headache, epileptic attack, conscious disturbance and visual disorder. Radiologic findings showed edema predominantly in the posterior cerebral white matter bilaterally, low density in CT, low signal in MRI T1WI, High signal in T2WI and Flair. The clinical manifestations and imaging lesions of 13 cases were both improved soon after treatment. Conclusion：The main clini- cal manifestations of PRES are headache, epileptic attack, conscious disturbance and visual disorder. The important physical sign of PRES is acute hypertension. Radiologic characteristic is edema mainly in the posterior cerebral white matter bilaterally, instand of infarctus,and most patients snap back after treatment.