CT对新生儿缺氧缺血性脑病的临床应用价值

Clinical Value of CT for Neonatal Hypoxic Ischemic Encephalopathy

目的:研究CT对新生儿缺氧缺血性脑病(HIE)的诊断及预后表现,探讨CT对该病的临床应用价值。方法:回顾分析40例临床及CT诊断为HIE病例的CT影像资料,所有病例均经系统治疗前、后CT检查。结果:40例患儿治疗前CT初诊脑轻度损害14例、中度损害17例、重度损害9例;系统治疗后随访复查CT显示脑轻度损害病例脑实质低密度范围逐渐缩小或消失,SAH吸收,直至完全恢复正常。中度损害恢复正常15例,余下2例及9例重度损害演变为脑软化、脑萎缩、脑积水、脑组织钙化等。结论:CT检查能真实反映HIE脑组织损害程度及动态变化,可为临床诊断、疗效观察及预后评价提供影像学依据。

Objective To study the clinical value of CT diagnosis and prognosis of hypoxic ischemic encephalopathy（HIE） in neonate.Methods Retrospective analysis of CT images of 40 cases diagnosed with HIE clinically or by CT was performed,and CT examinations were carried out before and after the systematic treatment.Results In the 40 cases,CT examination proved that there were 14 ones of mild brain injuries,17 ones of moderate injuries and 9 ones of severe injuries.The CT follow-up proved that for the patients with mild injuries,the low-density region shrinked or disappeared and SAH was absorbed,and that 15 patients with moderate injuries recovered,and that the remained 2 patients with moderated injuries and 9 ones with severe injuries progressed into encephalomalacia,brain atrophy,hydrocephalus,cerebral tissue calcification and etc.Conclusion CT examination can reflect the degree and dynamic changes of brain injuries of HIE,and thus can lay a foundation for clinical diagnosis as well as the evaluation of the curative effect and prognosis.