呋喃甾烷型皂甙的研究进展

Recent Progresses in Research of Furostanol Saponins

综述了呋喃甾烷型皂甙(双糖链甾体皂甙)的结构特点、化学性质、生理活性和生源合成。列举了1966～1999年发现的双糖链甾体皂甙,共214个。

Furostanol steroidal saponins, also called bidesmosidic steroidal saponins, typically bear two sugar chains at the 3 - and 26 - positions of the steroidal skeleton, respectively. They are widely distributed in the plant kingdom and have very diverse structures with a broad spectrum of biological and pharmacological activities. However, little attention has been given to this class of compounds until 1966, because of their structural complexity and liability associated with the unique opened F - ring structure. In this review, all ftlrostanol saponins, 214 in total, found through 1999 are listed. Their structures, physical and chemical properties, and biosynthetie routes are summarized.