薄层色谱法在蔗糖-6-苯甲酸酯合成过程中的应用

Application of Thin Layer Chromatography in Process of Preparation of Sucrose-6-benzoic Ester

用薄层层析法对蔗糖 - 6-苯甲酸酯合成过程中所涉及的反应物进行分离分析 ,选择优化出最佳展开剂体系为 :四氢呋喃∶丙酮∶水∶乙酸 =4∶ 6∶ 5∶0 .5(v/v)。在该展开剂条件下 ,可以有效地分离反应原料、反应中间体和反应产物 。

Thin layer chromatography was used to separate and analyze the compounds in process of preparation of sucrose 6 benzoic ester.The best developing solvent system is:tetramethylene oxide:acetone:water:acetic acid=4:6:5:0.5( V/V ).The reactants,mediates and products could be separated effectively, which indicated the reaction progress directly.