柚皮膳食纤维对高脂日粮大鼠血脂调节的影响

Regulatory Effect of Dietary Fiber from Citrus maxima Peel on Blood Lipids in Rats

研究柚皮膳食纤维(CDF)不同处理方式对高脂日粮大鼠抑制体质量和调节血脂等功能的影响。以SD大鼠为实验动物,随机分组并根据膳食纤维处理方法及剂量分为空白对照组(BCK)、高脂对照组(CK)、高脂饲料+超微粉碎0.2g/d组、高脂饲料+超微粉碎0.04g/d组、高脂饲料+挤压膨化超微粉碎0.2g/d组、高脂饲料+挤压膨化超微粉碎0.04g/d组,分别测定大鼠体质量、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)及动脉硬化指数(AI),并观察CDF对大鼠血脂水平的影响效果。结果表明:经挤压膨化后的超微粉碎组能显著降低大鼠血清中TC含量及AI值(P<0.05),但对大鼠的体质量、体脂百分率、LDL-C无明显影响(P>0.05)。经超微粉碎的高剂量柚皮膳食纤维具有良好的润肠通便和调节血脂作用。

The aim of this study was to observe the regulatory effect of dietary fiber from Citrus maxima peel on body weight and blood lipids in rats. SD rats were randomly divided into five groups including blank control （BCK）, high fat control （CK）, high fat diet ＋ 0.2 g/d of superfine dietary fiber powder （C1）, high fat diet ＋ 0.04 g/d of superfine dietary fiber powder （C2）, high fat diet ＋ 0.2 g/d of superfine powder of extruded dietary fiber （C3）, and high fat diet ＋ 0.04 g/d of superfine powder of extruded dietary fiber （C4）. Several blood indexes such as TC, TG, HDL-C, LDL-C and AI were detected and changes in blood lipids after 50 days of administration were observed. Compared with the CK group, the C4 groups showed a significant reduction in serum TC level and AI （P〈0.05）, though no significant differences in body weight, body fat content or serum LDL-C level were observed （P ：〉 0.05）. In conclusion, dietary fiber from Citrus maxima peel has laxative effects and can regulate blood lipids in mice.