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常压直接质谱分析技术快速诊断肺癌的应用 被引量:1

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摘要 目前手术中快速诊断肿瘤主要依靠冰冻切片,但该方法需冰冻、切片、染色等预处理,增加了麻醉和手术时间。常压直接质谱分析(AMS)可在无需复杂的样品预处理的情况下对各种样品进行快速检测分析。我们采用自制的甲醇萃取辅助的针尖电喷雾离子源检测肺癌及肺癌旁组织,利用主成分分析(PCA)能快速。(〈1min)区分肺癌及肺癌旁组织,为术中快速诊断肺癌提供一种新方法。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2013年第8期1560-1560,共1页 Chinese Journal of Experimental Surgery
基金 国家重大科学仪器设备开发专项基金资助项目(2011YQ170067) 国家自然科学基金资助项目(81160293)
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同被引文献9

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  • 8魏益平,鄢飞燕,贾滨,丁健桦,彭金华,陈焕文,徐建军.痰液直接电喷雾萃取电离质谱分析在非小细胞肺癌诊断中的应用[J].中华实验外科杂志,2011,28(3):422-424. 被引量:10
  • 9赵宗盛,徐建军,陈立如,温华,陈焕文,朱腾高,魏益平.尖端电喷雾萃取电离质谱技术诊断食管癌22例[J].世界华人消化杂志,2013,21(23):2320-2324. 被引量:3

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