家庭干预模式对以阴性症状为主的精神分裂症患者疗效的影响

Influence of family intervention mode in patients with schizophrenia characterized by negative symptoms

目的探讨家庭干预模式对以阴性症状为主的精神分裂症患者疗效的影响。方法将120例以阴性症状为主的精神分裂症患者随机分为观察组和对照组各60例，观察组在常规护理基础上予以家庭干预模式参与治疗，对照组实施常规护理。共观察12周，于治疗前及治疗6，12周末采用护士用住院患者观察量表（NOSIE）、阴性症状量表（SANS）评定其对精神分裂症患者疗效的影响。结果入院时2组患者NOSIE评分、SANS评分比较，无差异；治疗6周末和12周末，2组NOSIE评分、SANS评分及各因子分均优于治疗前，差异显著；观察组NOSIE评分、SANS评分及各因子分均优于对照组，差异显著。结论家庭干预模式能有效缓解精神分裂症患者的阴性症状，提高临床疗效，是辅助治疗慢性精神分裂症患者的一种有效方法。

Objective To evaluate the influence of family intervention mode in patients with schizophrenia characterized by negative symptoms. Methods A total of 120 cases of hospitalized patients with schizophrenia characterized by negative symptoms were randomly divided into the observation group and the control group with 60 cases in each group. The observation group received treatment through family intervention mode based upon routine care,while the control group used routine care. Influences were as- sessed with Nurses＇ Observation Scale for Inpatient Evaluation （NOSIE） and the Scale for Assessment of Negative Symptoms （SANS） before treatment and at the end of 6th ,12th week treatment. Results No significant difference of NOSIE score or SANS score were found upon admission between the observation group and the control group. At the end of the 6th week or the 12th week, total and all factors＇ scores of the NOSIE and SANS of both groups were better compared with pretreatment, the observation group was significantly better than the control group. Conclusions Family intervention model could significantly relieve the negative symptoms of schizophrenia, improve the patients＂ clinical efficacy and is an effective adjunctive therapy for schizophrenia.