两种洗液冲洗鼻腔对内镜鼻窦手术后疗效的对比

Comparison of postoperative effect between two cleansing solutions after endoscopic sinus surgery

目的观察内镜鼻窦手术后患者分别应用中药和西药两种不同成分洗液冲洗鼻腔的疗效。方法 75例接受功能性内镜鼻窦手术的慢性鼻及鼻窦炎患者于术后随机分成3组,一组用鼻渊通窍颗粒稀释液冲洗鼻腔,一组用鼻可乐洗鼻剂冲洗鼻腔,一组用生理盐水冲洗鼻腔。冲洗时间均持续到术后3个月,并分别于1、2、3个月在鼻内镜下观察鼻腔黏膜的恢复情况,行患者主观症状视觉模拟量表(visual analogue scale,VAS)评分和手术疗效评估。结果鼻渊通窍颗粒组和鼻可乐洗鼻剂组术后1个月VAS评分差异有统计学意义(t=2.516,P=0.015),手术疗效评估差异也有统计学意义(χ2=3.947,P=0.047),两组在术后2个月和3个月VAS评分差异和手术疗效评估差异均无统计学意义。结论短期内,内镜鼻窦手术后应用鼻可乐洗鼻剂的冲洗效果优于鼻渊通窍颗粒稀释液。

OBJECTIVE To compare the postoperative effect between two cleansing solutions after endoscopic sinus surgery.METHODS 75 cases diagnosed with chronic nasosinusitis were treated with functional endoscopic sinus surgery and were randomly divided into three groups.They were irrigated with granule diluent of Chinese medicine,Nasal Coke Nasal Douche and normal saline respectively after surgery.The curative time lasted 1 month to 3 months and operative effect was evaluated under nasal endoscope at 1,2 and 3 months,while subjective symptom was evaluated depending on visual analogue scale（VAS）.RESULTS Efficacy of Nasal Coke Nasal Douche was better than that of Chinese medicine only in the first month（by operative effect,t =2.516,P =0.015;by VAS,χ2=3.947,P =0.047）,but not at second month and third month.CONCLUSION Efficacy of Nasal Coke Nasal Douche was better than that of Chinese medicine in short period of time.