摘要
目的应用前节光学相干断层扫描仪(OCT),比较waveLightFS200飞秒激光与MoriaM290角膜板层切开刀制作角膜瓣的厚度及形态特点。方法前瞻性病例对照研究。对61例行双眼准分子激光原位角膜磨镶术(LASIK)的近视患者分别采用WaveLightFS200飞秒激光制瓣(WaveLight组,36例)和MoriaM290角膜板层切开刀制瓣(Moria组,25例)。术后1周,采用Visante前节OCT测量180°、90°、45°、135。轴位上距离角膜顶点0、±2、±3.5mm处的角膜瓣厚度。运用独立样本t检验对2组数据进行统计学分析。结果WaveLight组中央角膜瓣厚度为(105.53±5.86)μm,而Moria组为(132.96±13.91)μm(t=-13.16,P〈0.01)。WaveLight组中央角膜瓣精确度为(6.17±3.98)μm,而Moria组为(23.60±2.64)μm(t=-15.20,P〈0.01)。WaveLight组角膜瓣均匀性指数为(4.07_+0.94)μm,Moria组为(8.48±2.35)μm(t=12.60,P〈0.01)。WaveLight组角膜瓣的对称性指数[(33.81±11.28)μm]明显小于Moria组[(68.46±26.66)μm],差异有统计学意义(t=8.67,P〈0.01)。结论前节OCT显示WaveLightFS200飞秒激光制作的角膜瓣与MoriaM290角膜板层切开刀相比,中央厚度更精确、重复性更好,角膜瓣形态更均匀。
Objective To evaluate and compare the thickness and morphology of laser in situ keratomileusis (LASIK) flaps created by either the WaveLight FS-200 femtosecond laser or the Moria microkeratome M2 90 using anterior segment optical coherence tomography (AS-OCT). Methods This was a prospective case-control study. Bilateral LASIK was performed on 61 myopic patients. Flaps were created using the WaveLight FS-200 femtosecond laser in 72 eyes and the Moria M2 90 microkeratome in 50 eyes. The thickness at 17 points across each flap, 0 mm, +2 mm, and +3.5 mm to the corneal vertex on the horizontal, vertical, 45°and 135° meridians, were evaluated using a Visante AS-OCT at 1 week postoperatively. An independent t test was used. Results The central flap thickness of the WaveLight group was 105.53±5.86μm, while it was 132.96±13.91 μm in the Moria group (t=-13,16, P〈0.01). The difference between the achieved and the intended flap thickness (accuracy) was 6.17±3.98 μm and 23.60±12.64μm, respectively (t=-15.20, P〈0.01). The standard deviation of thickness in the 17 points within an individual flap (uniformity) was 4.07±0.94 μm in the WaveLight group and 8.48±2.35 μm in the Moria group (t=-12.60, P〈0.01). The index S (Symmetry) of Moria group (33.81±11.28μm) was significantly smaller in the WaveLight group (68.46±26.66μm) (t=-8.67, P〈0.01). Conclusion AS-OCT showed that the flaps created with the WaveLight FS-200 femtosecond laser were more accurate, reproducible, and uniform than those created with the Moria M2 90 microkeratome.
出处
《中华眼视光学与视觉科学杂志》
CAS
2013年第7期401-404,共4页
Chinese Journal Of Optometry Ophthalmology And Visual Science
关键词
飞秒激光
角膜瓣
角膜磨镶术
激光原位
体层摄影术
光学相干
前节
Femtosecond laser
Corneal flap
Keratomileusis,laser in situ
Tomography, optical coherence, anterior segment