三阴性乳腺癌的MRI研究进展

Research progresses of MRI for triple-negative breast cancer

目的三阴性乳腺癌(TNBC)具有特殊的生物学行为及临床病理学特征,临床缺乏有效治疗方法,预后较差。目前MRI是诊断乳腺癌的最准确的影像学方法。MRI有助于诊断TNBC、制订治疗方案与预后评估,并能加深对其生物学行为的理解。TNBC的MRI特征包括较大的单发病灶,边缘光滑,T2WI呈高信号,增强后环形强化;而动态对比增强MRI(DCE-MRI)、DWI及MRS对于TNBC的临床应用价值有待更深入研究。

Triple-negative breast cancer （TNBC）, which characterized by distinct biological and clinical pathological features, has a worse prognosis because the lack of effective therapeutic targets. Breast MR is the most accurate imaging modality for diagnosis of breast cancer currently. MR imaging recognition could assist in diagnosis, pretreatment planning and prognosis evaluation of TNBC, as well as adding to understanding of the biological behavior of TNBC. MR findings of a large solitary lesion, mass with smooth margin, high signal intensity on T2WI and rim enhancement are typical MRI features associated with TNBC. Further work is necessary about the clinical application of dynamic contrast-enhanced MR imaging （DCE-MRI）, DWI and MRS.