期刊文献+

环形RNAs:microRNAs的新靶标

下载PDF
导出
摘要 微RNAs(microRNAs,miRNAs)作为一类重要的基因表达调控分子已得到了生命科学领域的广泛关注.它们主要通过与mRNA的3’非翻译区(UTR)结合,发挥诱导mRNA降解或抑制翻译的功能.随着研究不断深入,
出处 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 2013年第8期728-730,共3页 Progress In Biochemistry and Biophysics
基金 国家自然科学基金资助项目(81101373 81270511 81200406) 黑龙江省博士后资助经费(LBH-Z12172)
  • 相关文献

参考文献14

  • 1Orom U A, Nielsen F C, Lund A H. MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation.Mol Cell, 2008, 30(4): 460-471.
  • 2Tay Y, Zhang J, Thomson A M, et al. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature, 2008, 455(7216): 1124-1128.
  • 3Eiring A M, Harb J G, Neviani P, et al. miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell, 2010, 140(5): 652-665.
  • 4Kim D H, Saetrom P, Sncve O Jr, et cd. MieroRNA-directed transcriptional gene silencing in mammalian cells. Proc Natl Acad SciUSA, 200g, 21; 105(42): 16230-16235.
  • 5Ma N, Xiang Y, Zhang Y, et ed. A microRNA "target pools" remains mysterious. J Cell Biochem, 2012, 113(1): 1-2.
  • 6Hansen T B, Jensen T I, Clausen B H, et d. Natural RNA circles function as efficient microRNA sponges. Nature, 2013, 495(7441): 384-388.
  • 7Memezak S, Jens M, Elefsinioti A, et al. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature, 2013, 495(7441): 333-338.
  • 8Salzman J, Gawad C, Wang P L, et d. Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types. PLoS One, 2012, 7(2): e30733.
  • 9Poliseno L, Salmena L, Zhang J, et d. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature, 2010, 465(7301): 1033-1038.
  • 10Franco-Zorrilla J M, Valli A, Todesco M, et al. Target mimicry provides a new mechanism for regulation of microRNA activity. Nat Genet, 2007, 39(8): 1033-1037.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部