66例糖尿病足临床特征分析

Clinical characteristics analysis of 66 cases of diabetic foot patients

目的对糖尿病足(DF)患者临床资料进行分析,探讨糖尿病足发生的临床特征、危险因素,指导临床进行有效的防治,提高其治愈率。方法对2010年1月～2011年5月在川北医学院附属医院DF患者66临床资料的平均血糖(MBG)、糖化血红蛋白(HbA1c)、白细胞总数(WBC)、白蛋白(ALB)、血脂、双下肢血管彩色多普勒超声(CDU)、病原菌培养及药敏试验等指标进行回顾性分析。结果 DF患者MBG为(16.9±7.1)mmol/L,HbA1c为(10.7±3.6)%,ALB为(31.7±7.3)g/L,WBC为(10.8±7.2)×109/L,三酰甘油(TG)为(1.39±0.59)mmol/L,总胆固醇(TC)为(4.08±1.32)mmol/L,低密度脂蛋白胆固醇(LDL-C)为(2.35±0.95)mmol/L,高密度脂蛋白胆固醇(HDL-C)为(1.06±0.36)mmol/L,双下肢血管CDU异常52例(78.8%),分离培养病原菌共62株,G+菌36株(58.1%),G-菌24株(38.7%),真菌2株(3.2%),G+菌对万古霉素、磺胺类、利奈唑烷等敏感,G-菌对亚胺培南、氨基糖苷类等敏感。结论糖尿病足重在预防、早期治疗,以降低截肢率,减少医疗费用,提高糖尿病患者的生活质量。

Objective To analyze the clinical data of diabetic foot（DF） patients,to explore the clinical characteristics,risk factors with DF,clinical guidance for effective prevention and control,to improve the cure rate.Methods 66 cases of DF From January 2010 to May 2011 in Affiliated Hospital of North Sichuan Medical College were selected and the clinical data were analyzed,such as MBG,HbA1c,WBC,ALB,blood lipidst,the blood vessels of CDU of lower limb,pathogenic bacteria culture,drug sensitive test were analyzed.Results MBG of DF patients was（16.9 ±7.1） mmol/L,HbA1c was（10.7±3.6）%,ALB was（31.7±7.3） g/L,WBC was（10.8 ±7.2）×109/L,TG was（1.39±0.59） mmol/L,TC was（4.08±1.32） mmol/L,LDL-C was（2.35 ±0.95） mmol/L,HDL-C was（1.06±0.36） mmol/L.52 cases（78.8%） of double lower extremities abnormal vascular CDU were found,a total of 62 strains were found,36 strains（58.1%） G＋ bacteria were found,24 strains（38.7%） of G-bacteria were found,2 strains（3.2%） of fungus were found;G＋ bacteria were sensitive to vancomycin,sulfa,rina thiazole alkanes;G-bacteria were sensitive to imipenem,aminoglycoside.Conclusion DF is focusing on prevention and early treatment in order to reduce the amputation rate and reduce the costs,improve the quality of life in patients with diabetes.