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雷米普利在急性心肌梗死中的应用——由AIRE和AIREX研究谈起 被引量:1

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摘要 80年代末期,急性心肌梗死(AMI)应用溶栓药物、阿司匹林、β-受体阻滞剂治疗,获得很大成绩,存活率明显增加。但仍有相当一部分病人出现严重心力衰竭、再发心肌梗死和死亡。西方国家全面开展了对AMI患者应用血管紧张素转换酶(ACE)抑制剂的随机、双盲、安慰剂对照的多中心临床试验,评价其作用。其中开始于1989年的AIRE和AIREX试验是应用雷米普利(Ramipril)或安慰剂治疗急性心肌梗死后心力衰竭的随访研究。
作者 吴学思
出处 《中国医药导刊》 2000年第2期10-13,共4页 Chinese Journal of Medicinal Guide
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  • 1The Acute Infarction RamiprilEfficacy (AIRE) Study Investigators. Effect of ramipril on mortality and morbidity ofsurvivors of acute myocardial infarction with clinical evidence of heart failure. TheLancet, 1993, 342: 821~828
  • 2HhallA,MurrayGD,BallSG,etal.(AIREXStudyInvestigators).TheLancet,1997,349:1493-1497
  • 3Yusuf S, Zucker D, Peduzzi P, et al. Effect of coronary artery bypass graft surgeryon survival: overview of 10 years results from randomised trials by the Coronary ArteryBypass Graft Surgery Trialists Collaboration. Lancet, 1994, 344: 563~570
  • 4GISSI-3. (Gruppo Italiano per lo Studio della Sopravvivenza_nell' InfartoMiocardico). Effects of lisinopril and transdermal glyceryl trinitrate singly and togetheron 6-week mortality and ventricular function after acyte myicardial infarction. Lancet,1994, 343: 1115~1122
  • 5ISIS-4 gollaborative Group. Fourth International Study of Infarct Survivai. Allrandomised factorial trial assessing early oral captopri, oral mononitrate, andintravenous magnesium sulphate in 58 050 patients with suspected acute myocardialinfarction. Lancet, 1995, 345: 669~685
  • 6The SOLVD Investigators. Effect of enalapril on survival in patients with reducedleft ventricular ejection fraction and congestive heart failure. N Engl J Med, 1991, 325:293~302
  • 7Swedberg'K, Held R. Cjekshus J, Rasmussen K, Ryden L, Wedel H on behaif of theCONSENSUS Ⅱ Study Group. Effects of the early administration of enalapril on mortalityin patients with acute myocardial infarction. Results of the Cooperative New ScandinavianEnalapril Survival Study Ⅱ (CONSENSUS Ⅱ). N Engl J Med 1992; 327: 678~684.
  • 8Liu LS, Wang W, et al. For the Chinese Cardiac Study Collaborative Group. Oralcaptopril versus placebo among 13 634 patients with suspected acute myocardial infarction:interim report from the Chinese Cardiac Study (CCS-1). Lancet, 1995, 345: 686~687
  • 9Pfeffer MA, Braunwald E, Moye LA, et al. On behalf of the SAVE Investigators.Effect of captopril on mortality and morbidity in patients with left ventriculardysfunction after myocardial infarction. N Engl J Med, 1992; 327: 669~677
  • 10Kober L, Torp-Pedersen C, Carlsen JE, et al for the Trandolapril CardiacEvaluation (TRACE) Study group. A clinical trial of the angiotension-converting-enzymeinhibitor trandolapril in patients with left ventricular dysfunction afar myocardialinfarction. N Engl J Med, 1995, 333: 1670~1676

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