血尿酸、超敏C反应蛋白与冠心病的相关性分析

Correlation Analysis of Uric Acid and High Sensitivity C-reactive Protein in Patients with Coronary Heart Disease

目的观察血尿酸、超敏C反应蛋白(hs-CRP)在冠心病患者中的表达情况,并分析其与冠心病发生的相关性。方法选取117例冠状动脉造影确诊为冠心病的患者作为观察组,同期选择判定为非冠心病的108例住院患者作为对照组。检测并比较两组患者的血尿酸、hs-CRP的水平。结果观察组hs-CRP水平显著高于对照组,且血尿酸水平也显著高于对照组(P<0.05)。结论血尿酸水平及hs-CRP是预测冠心病的重要生化指标,与其他危险因素共同作用时可导致冠心病的发生,对于冠心病严重程度的判断及预测有重大意义,值得临床上进一步研究和推广。

Objective To observe blood uric acid and high sensitive C-reactive protein（hs-CRP） expression in patients with coronary heart disease,and analyze its correlation with coronary heart disease.Methods One hundred and seventeen cases of coronary angiography diagnosed coronary heart disease were selected as the observation group and 108 hospitalized non-coronary heart disease patients of the same period were selected as the control group.Blood uric acid,hs-CRP level of the two groups were compared.Results hs-CRP and the serum uric acid levels of the observation group were significantly higher than the control group（P 0.05）.Conclusion The blood levels of uric acid and hs-CRP are important biochemical parameters,together with other risk factors can lead to the occurrence of coronary heart disease,which is of great significance for the severity judgment and forecast,worthy of further study and promotion in clinical.