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托烷司琼联合地塞米松预防乳腺癌化疗致恶心呕吐的临床研究 被引量:8

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摘要 目的:评价盐酸托烷司琼联合地塞米松对乳腺癌化疗引起的恶心、呕吐的有效性和安全性。方法:80例乳腺癌化疗患者分为治疗组40例,对照组40例,治疗组于化疗前30min静脉滴注盐酸托烷司琼5mg,联合静脉注射地塞米松5mg,对照组于化疗前30min静脉滴注盐酸托烷司琼5mg,按WHO标准评价化疗期间引起的恶心、呕吐的反应。结果:治疗组的恶心、呕吐完全控制率和有效率均明显高于对照组,差异有统计学意义(P<0.05)。结论:盐酸托烷司琼与地塞米松联合应用可以明显减轻乳腺患者化疗所致的恶心、呕吐反应,且安全性较高。
出处 《河北医学》 CAS 2013年第9期1384-1386,共3页 Hebei Medicine
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