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BNIP3在细胞凋亡与自噬中的作用 被引量：6

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摘要 BNIP3属于Bcl-2家族蛋白中的BH3-only亚家族,其结构、细胞内定位、对细胞生存的调控与BH3-only亚家族的其他蛋白不尽相同。近年来研究发现,BNIP3不仅参与细胞的凋亡,同时调控细胞自噬和坏死等过程。在不同的外界环境下,其调控方式和作用效应也不尽相同,其调控方式的复杂性预示着其生物学活性的多样性。阐明其作用机制对于理解和控制多种病理、生理过程具有重要意义。本文就BNIP3在细胞凋亡与自噬中的作用作一综述。
作者 徐冉 魏珑珑 李志强 李晓锋 韩丽辉
机构地区 山东大学医学院 安丘市立医院
出处 《山东医药》 CAS 2013年第28期105-108,共4页 Shandong Medical Journal
基金 山东大学大学生科技创新基金项目(2011473)
关键词 BNIP3 凋亡 自噬 细胞
分类号 R329.2 [医药卫生—人体解剖和组织胚胎学]
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参考文献21

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二级参考文献70

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共引文献5

同被引文献94

  • 1王苹苹,孔繁平,陈学群,杜继曾.低氧细胞应激的HIF-1信号通路[J].浙江大学学报（医学版）,2011,40(5):559-566. 被引量：71
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引证文献6

二级引证文献28

山东医药
2013年 第28期

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