摘要
目的 探讨中风患者急性期NO与SOD变化的特点及相关关系。方法 采用硝酸还原酶法及黄嘌呤氧化酶法对 118例急性期中风患者和 54例正常对照组进行血清NO与SOD含量测定 ,并对其中 4 0份病例进行治疗前后动态观察。结果 急性期中风患者无论是缺血性还是出血性血清NO与SOD水平均显著高于正常对照组 (P均 <0 .0 1) ,但两组之间无统计学意义 (P >0 .0 5) ,4 0份病例治疗前后NO与SOD亦有显著性差异 (P均 <0 .0 1) 。结论 急性期脑中风患者NO与SOD均参与人体生理病理反应。
Objective To explore the change character of the serum NO and SOD in the patients with acute cerebralapoplexy and the relationship between the change and the disease.Methods Using the nitrate reductase method and xanthine oxidase method,the serum NO and SOD of 118 patients of acute cerebralapoplexy and 54 normal people were measured.And the serum parameters in 40 patients were observed dynamically before and after the therapy.Results No matter the acute cerebralapoplexy is ischemic or hemorrhagic,the serum NO and SOD of the patiemts were higher than which in the normal people (P<0.01) .But there is no statistically significant difference between ischemic and hemorrhagic groups (P>0.05) .The significant changes of the serum NO and SOD in the 40 patients were observed between before and after the therapy (P<0.01) .Conclusion The study show that both of the serum NO and SOD take part in the physiopathological reaction in the patients with acute cerebralapoplexy.[
出处
《深圳中西医结合杂志》
2000年第4期159-160,共2页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine