摘要
了解抗结核药物副作用发生情况。方法 对 1990～ 1998年住院肺结核患者 184 8例进行临床分析。结果 抗结核药物副作用 6 0 4例 (32 .7% ) ,以肝损害、位听神经损害、血液学异常及胃肠反应为主 (82 .1% ) ,因副作用致终止治疗率 14.6 %。 77%的副作用出现于给药的 2个月内 ,血液学异常的 50 %以上在用药的 3个月后出现。结论 抗结核药物引起的副作用常见 ,分布较广 ,应引起临床工作者高度重视。
Objective To illustrate the side effects of antituberculous agents.Methods The clinincal data of pulmonary tuberculosis patients during 1990～1998 were analyzed.Results Various side effects resulting from antituberculous agents were confirmed in 604 cases (32.7%),liver injury,acoustic nerve injury,blood system injury,gastrointestinal response of them were primary (82.1%).Stopped treatment rate was 14.6%.77% in side effects occurred within 2 months after administration,but the blood system injury occurred after 3 months.Conclusion The side effects of antituberculous agents were common and extensive in distribution,clinical doctors must think highly of the matter.
出处
《中国防痨杂志》
CAS
2000年第3期154-156,共3页
Chinese Journal of Antituberculosis
