摘要
目的探讨女性不孕患者与血清生殖激素及染色体核型的关系。方法对不孕患者进行外周血淋巴细胞培养,G显带进行染色体核型分析,并进行血清生殖激素检测,并对结果进行比较分析。结果 986例女性不孕患者中检出染色体异常核型61例,异常率为6.19%(61/986)。61例染色体异常患者中常染色体异常39例,占65.93%(39/61);性染色体异常22例,占36.07%(22/61)。不孕组黄体生成素(LH)、促卵泡成熟激素(FSH)、垂体泌乳素(PRL)、雌二醇(E2)、睾酮(T)与对照组比较,差异有统计学意义(P<0.05),孕酮(P)与对照组相比差异无统计学意义(P>0.05)。结论对女性不孕患者做染色体检查和性激素检测是必要的,为诊断和治疗提供重要依据。
Objectives： To investigate the relationship between occurrence of female patients with infertility and parameters of chromosome,reproduction hormone.Methods： To gather patients’peripheral blood and carry on cultivating,to make chromosome G-banding and karyotype analysis.To test and analyze reproduction hormone level of female patients with infertility.Results： The number of abnormal chromosomes is 61 cases（6.19%）.The number of abnormal euchromosomes is 39cases,accounting for 65.93%（39 /61） of the total abnormal chromosomes,while the number of abnormal sex chromosomes is 22,accounting for 36.07%（22 /61）.The difference of LH,FSH,PRL,E2and T between patiens and the control group has statistics significance（P 0.05）,the difference of P between two groups is non-statistics significance（P 0.05）.Conclusion： It is necessary for female patients with infertility to take chromosome and semen hormone tests.This will provide important reference for diagnositic and treatment.
出处
《中国优生与遗传杂志》
2013年第8期70-71,68,共3页
Chinese Journal of Birth Health & Heredity
关键词
不孕症
染色体
生殖激素
Sterility
Chromosome
Reproduction hormone
