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孕周选择对唐氏综合征筛查效率的影响 被引量:2

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摘要 目的分析本地区各孕周唐氏征筛查人群年龄、体重、孕次等分布情况,对孕周与产前筛查效率的关系进行分析,以期发现本地区效率较高的筛查孕周或孕周段。方法回顾性分析本院5179例孕16~20+6周产前筛查的孕妇三联血清标志物检测结果,对筛查出唐氏综合征高风险孕妇行羊水细胞染色体检查确诊。结果筛查人群年龄、体重呈正态分布,不同孕周筛查人群的年龄构成和孕次构成无统计学意义;体重随着孕周的增加而增加。孕周与唐氏生筛查的假阳性率有相关性,16-18+6孕周段假阳性率低于其他孕周段。结论筛查年龄、体重和孕次分布对筛查效率无明显影响,筛查最佳孕周段为16-18+6周。
作者 杨柳 刘鸿春
出处 《中国优生与遗传杂志》 2013年第8期74-75,共2页 Chinese Journal of Birth Health & Heredity
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参考文献4

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