摘要
目的探讨潍坊市新生儿先天性甲状腺功能低下(CH)和苯丙酮尿症(PKU)的发病率,治疗方法及干预效果,为CH和PKU治疗与干预提供依据。方法新生儿出生72h后采足跟血,用流式荧光法检测PHE含量,用酶联免疫吸附试验测血片中TSH浓度。结果活产儿67 259例,新生儿疾病筛查实验53 250例,筛查率79.2%;CH 12例,检出率1/4438;PKU 8例,检出率1/6656。结论新生儿CH和PKU经筛查可早发现,早诊断,早治疗及干预,从而使患儿生长发育指标,智能达到同龄水平。
Objective: Investigate Weifang city of neonatal congenital hypothyroidism(CH) and phenylketonuria(PKU) morbidity,treatment methods and effect of intervention,as CH and PKU treatment and intervention for them.Methods: The neonatal 72h heel blood after mining,with flow cytometry assay for detection of PHE content,using enzyme-linked immunosorbent assay for measuring TSH concentration in blood.Results: Live births in 67 259 cases,53 250 cases of newborn disease screening tests,screening rate of 79.2%;in 12 cases of CH,the detection rate of 1 /4438;PKU 8 cases,1 /6656.Conclusion: The detection rate of neonatal CH and PKU through screening early detection,early diagnosis,early treatment and intervention,so that the children growth index,AI reach the age level.
出处
《中国优生与遗传杂志》
2013年第8期92-92,7,共2页
Chinese Journal of Birth Health & Heredity