摘要
1目的 了解银屑病病人 T淋巴细胞免疫功能状况。 2方法 采用免疫酶技术和淋巴细胞培养法 ,对 5 4例进行期重症寻常型银屑病病人和 2 0例正常人外周血 T淋巴细胞亚群及白细胞介素 2受体α(m IL - 2 Rα)进行检测。 3结果 5 4例病人外周血 CD+ 3,CD+ 4 ,CD+ 8细胞百分率、CD+ 4 /CD+ 8比值和 m IL - 2 Rα表达率均明显低于正常人 ,差异有极显著性 (t=2 .99～ 9.2 9,P均 <0 .0 1)。 4结论 进行期重症寻常型银屑病病人 T淋巴细胞免疫功能明显低下。
Objective To know about the immunologic function of T lymphocytes of patients with psoriasis. Methods Immunoenzymatic technique and lymphocyte culture were used to determine T lymphocyte subpopulations and mIL 2Rα in 54 patients with severe psoriasis vulgaris at active stage. Results The percentage of CD + 3,CD + 4,CD + 8 cells, the ratio of CD + 4/CD + 8 and the rate of expression of mIL 2Rα in the peripheral blood of patients were significantly lower than that of healthy persons (t=2.99-9.29, P<0.01). Conclusion The immunologic function of T lymphocytes was lower in psoriasis patients than that of healthy persons.;[
出处
《青岛大学医学院学报》
CAS
2000年第1期62-63,共2页
Acta Academiae Medicinae Qingdao Universitatis
