酪酸杆菌双歧杆菌二联活菌联合马来酸曲美布汀治疗急性胃肠炎疗效观察

Curative effect of butyric acid bacteria bifidobacteria duplex living bacterium combined with trimebutine in treating acute gastroenteritis

目的评价酪酸杆菌双歧杆菌二联活菌联合马来酸曲美布汀治疗急性胃肠炎疗效。方法 98例急性胃肠炎患者随机分成两组,治疗组51例,口服酪酸杆菌双歧杆菌二联活菌+马来酸曲美布汀。对照组47例,口服酪酸杆菌双歧杆菌二联活菌。两组疗程均为3 d,分别比较两组治疗前后临床症状,并在治疗结束时进行临床疗效评价。结果治疗组疗效较对照组有明显改善,治疗组总有效率为94.12%;对照组总有效率为80.85%,两组比较差异有显著性(P<0.05)。治疗组用药后症状明显较本组治疗前改善,与对照组治疗后比较,差异有显著性(P<0.05))。结论双歧三联活菌与马来酸曲美布汀联合治疗急性胃肠炎疗效满意。

Objective To investigate the curative effect of butyric acid bacteria bifidobacteria duplex living bacterium combined with trimebutine in treating acute gastroenteritis.Methods 98 patients with acute gastroenteritis were assigned into two groups randomly： 51 patients as treatment group treated with butyric acid bacteria bifidobacteria duplex living bacterium combined with trimebutine,47 patients as control group treated with butyric acid bacteria bifidobacteria duplex living bacterium alone.The clinical symptoms of two groups were compared before and after treatment,respectively,and clinical efficacy was evaluated after treatment.Results The symptoms of treatment group were significantly improved than that of control group.The total effective rate of treatment group（94.12%） was significantly higher than that of the control（80.85%）（P 0.05）.Conclusion Combination of butyric acid bacteria bifidobacteria duplex living bacterium combined with trimebutine can provide a satisfactory curative effect for patients with acute gastroenteritis.