锦灯笼联合双黄连治疗小儿疱疹性咽峡炎临床观察

The clinical observation of Phycalis alkekengi plus Shuanghanlian in treatment of infantile herpangina

目的观察锦灯笼代茶饮加双黄连(注射剂)雾化吸入治疗小儿疱疹性咽峡炎的临床疗效。方法将60例疱疹性咽峡炎患儿随机分为对照组和治疗组,对照组采用更昔洛韦5 mg/(kg.d)静脉滴注及退热、镇静等对症治疗;治疗组在此基础上,用锦灯笼代茶饮加双黄连(注射剂)雾化吸入。结果治疗组在退热、精神状态、咽峡部疱疹情况等方面均优于对照组,有效率与对照组比较差异有统计学意义(P<0.05)。结论锦灯笼代茶饮加双黄连(注射剂)雾化吸入治疗小儿疱疹性咽峡炎疗效显著、无明显不良反应、缩短了病程,是一种有效、安全的治疗方法,值得临床借鉴。

ObjectiveTo observe the clinical efficacy of atomizing inhalation of Physalis alkekengi tea plus Shuanghuanglian （injection） in treating infantile herpangina. MethodsSixty patients were divided into control group and treatment group, the control group used ganciclovir 5 mg/（kg·d） oral or intravenous infusion and antipyretic, sedative and other symptomatic treatment. The treatment group based on the use of Physalis alkekengi,on behalf of the tea with Shuanghuanglian inhalation. ResultsThe treatment group in the fever, mental state, pharyngeal herpes conditions were better than the control group, there was statistically significant efficiency compared with the control group （P〈005）. ConclusionPhysalis alkekengi tea plus Shuanghuanglian （injection） inhalation is an effective and safe treatment for children with herpetic angina, no significant adverse reactions. This treatment can shorten the course of disease, and worthy of clinical application.