食道癌发病因素病例对照研究

A case-control study on pathologic factors of esophageal cancer

目的 探讨山西省食道癌发病因素的模式及其变迁。方法 采用流行病学成组频数匹配的病例对照研究方法进行了调查。结果 病前 10～ 2 0 a间食肉频数少、细粮比例小、快食、吸烟和食道癌家族史为食道癌的发病因素 ,且这些因素之间有明显的协同作用。结论 针对上述因素尤其有交互作用的因素进行预防可降低该病的发病率。

Objective To probe into the patterns and changes of pathogenic factors of esophageal cancer (EC) in Shanxi Province.Method The methods of epidemiological grouping,frequency distribution,and matched control were used in this study.Results The data showed that during the period of ten to twenty years before the invasion,those who had a less flesh-eating,a lower dietary ratio of fine food grain,tachyphagia,smoking,as well as a family history of EC,are regarded as getting more risk factors of EC;and moreover,a synergetic action exists noticeably among these factors.Conclusion Aiming at the aforesaid factors,especially those with interactions among them,the paper suggests that taking suitable preventive measures must make a decrease in the EC incidence.