干扰素雾化治疗小儿病毒性上呼吸道感染疗效观察

Observation on the effect of Interferon aerosol in treating infantile viral upper respiratory tract infection

目的 观察干扰素雾化治疗小儿病毒性上呼吸道感染的临床疗效.方法 选取60例上呼吸道感染患儿,按照抽签方法分为两组,观察组采用干扰素-α1b高频雾化进行治疗,对照组采用利巴韦林注射液治疗,两组疗程均为7d,疗程结束后比较临床疗效.结果 观察组总有效率为90％,对照组总有效率为70％,观察组总有效率显著高于对照组（Х^2=5.684,P＜0.05）；观察组患儿退烧时间为（16.39±5.34）h,对照组患儿退烧时间为（32.37±8.14）h,观察组退烧时间明显短于对照组（t=3.584,P＜0.05）.结论 干扰素雾化治疗小儿病毒性上呼吸道感染,具有显著的疗效,且能够有效减少不良反应,提高安全度,在临床中是一种值得推荐的方法.

Objective To observe the clinical effect of interferon aerpsp; in the treatment of pediatric viral upper respiratory tract infection disease.Methods 60 children with upper respiratory tract infection were divided randomly into two groups.The observation group were treated with interferon-α1b high atomization treatment of patients in the control group,with ribavirin injection treatment,two groups of patients were treated for 7 days.After a comparison of clinical outcomes.Results The total efficiency of the observation group was 90%,which was significantly higher than that of the control group（70%） （Х^2 =5.684,P 〈0.05） ; The fever retrcating time in observation group was （16.39 ± 5.34） h,whichwas significantly shorter than that in control group[（16.39 ± 5.34） h] （t =3.584,P 〈 0.05）.Conclusion For children virus upper respiratory tract infection treated by interferon treatment,atomization,having remarkable curative effect,and can effectively reduce the adverse reaction,enhance safety,clinical is a recommendable method.