局部应用抗生素对86例患者术后早期手术部位感染的疗效研究

Curative effect of topical application of antibiotics on early stage of surgical site infection in 86 cases

目的探讨局部应用抗生素对患者术后早期手术部位感染(SSI)的临床效果。方法回顾性分析2006—2011年对86例术后患者的治疗,分别根据局部是否应用抗生素分为处理组及对照组,各43例。处理组以利多卡因10 mL稀释2.0 g头孢拉定后,沿切口外红肿处周围由浅至深层逐渐注射,循切口外红肿处周围刺入皮下,均匀将药液浸润注射于切口周围,每天1次,局部辅助特定电磁波谱治疗仪(TDP)治疗;对照组仅局部辅助TDP治疗,比较两组处理后SSI发生率。结果对照组SSI发生率为25.58%(11/43),处理组SSI发生率为4.65%(2/43),两组比较,差异有统计学意义(P<0.05)。结论局部应用抗生素能有效控制患者术后早期SSI。

Objective To investigate the clinical effect of topical application of antibiotics on early stage of surgical site infection（SSI）.Methods 86 patients with early postoperative stage during 2006-2011 were retrospectively analyzed and randomly divided into the treatment group and the control group according to whether the topical application of antibiotics was per formed,43 cases in each group.In the treatment group,cephradine 2.0 g diluted with lidocaine 10 mL was gradually injected around swelling outside the incision from shallow to deep layers,piercing into the skin around swelling outside the incision,uniformly infiltrating the liquid around the incision,once a day,and local auxiliary TDP treatment was assisted;in the control group,only local auxiliary TDP treatment was used.The incidence rates of SSI after treatment were compared between the two groups.Results The SSI incidence rate was 25.58%（11/43）in the control group and 4.65%（2/43） in the treatment group respectively,the difference was statistically significant（P0.05）.Conclusion Topical application of antibiotics can effectively control early stage of SSI.