住院患儿肺炎支原体感染状况

Mycoplasma pneumoniaeinfection in hospitalized children

目的:了解住院患儿肺炎支原体的感染率及流行特征。方法:采用ELISA法对2010～2012年在我科住院的2 332例患儿取静脉血检测肺炎支原体特异性抗体IgM(MP-IgM)。结果:3年共检测阳性例数418例,阳性率为17.92%,其中<1岁52例,～3岁158例,～7岁135例,>7岁73例,男女发病及季节上无明显差异(P>0.05),而各年龄组、上呼吸道感染和下呼吸道感染中有明显差异(P<0.05),肺外表现有116例(27.75%)。结论:肺炎支原体感染率随着年龄的增长而增加,为下呼吸道感染的主要病原体,部分伴有呼吸道外的器官损害,在治疗上大环内酯类抗生素有较好的疗效。

Objective：To understand the incidence of Mycoplasma pneumoniae infection in hospitalized children and its epidemiological characteristics.Methods：Venous blood were collected from 2332 hospitalized children for detection of Mycoplasma pneumoniae antibody IgM（MP-IgM）by ELISA method.Results：A total of 418cases were detected as positive showing apositive rate of 17.92%,of which,52 cases were younger than 1year old,158were 1-3years old,135were 3-7years old and 73cases were older than 7years old.No significant difference in the incidence were found between female and male cases or between different seasons;however,within the same age group,significant difference was observed between cases with upper respiratory tract infections and those with lower respiratory tract infections.A total of 116cases（27.75%）showed extrapulmonary manifestations.Conclusion：Incidence of Mycoplasma pneumoniaeinfection,which is the main strain causing lower respiratory tract infection,increases with age,and some of the infections are accompanied by damages in extrapulmonary organs.Macrolide antibiotics are effective on the infection.