津力达颗粒治疗2型糖尿病的疗效与安全性评价

Efficacy and Safety of Jinlida Granules for Type 2 Diabetes

目的:通过文献荟萃分析,评价津力达颗粒治疗2型糖尿病的疗效与安全性。方法:利用文献检索法检索相关文献,采用RevMan 4.2进行Meta分析,比较治疗组和对照组治疗前后的空腹血糖(FPG)、餐后2 h血糖(2hPG)、糖化血红蛋白(HbA1c)及不良反应等指标。结果:治疗前,治疗组的FPG、2hPG、HbA1c与对照组比较无统计学差异(P>0.05);治疗后,治疗组的FPG、2hPG、HbA1c明显低于对照组(P<0.01);未发现治疗组存在严重不良反应。结论:津力达颗粒联合西药治疗2型糖尿病临床疗效显著,未发现严重不良反应,安全性较好,值得临床推广使用。

OBJECTIVE ：To evaluate the efficacy and safety of Jinlida granules for type 2 diabetes through recta- analysis of literature. METHODS： The pertinent literature was retrieved using literature retrieval method and the included literature was given recta-analysis using RevMan 4.2 statistical software, with the levels of fasting plasma glucose （FPG） , 2h postprandial glucose （2hPG） and glycosylated hemoglobin Alc （HbAlc） and adverse reactions in the treatment group and the control group analyzed and compared before and after treatment. RESULTS： Before treatment, there were no statistically significant differences with regard to FPG, 2hPG and HbAlc levels between the treatment group and the control group （ P 〉 0. 05 ） ; after treatment, FPG, 2hPG and HbA1 c levels in the treatment group were significantly lower than in the control group （ P 〈 0. 01 ）. No severe adverse reactions were noted in the treatment group. CONCLUSION： Jinlida granules combined with western medicine resulted in remarkable clinical efficacy in the treatment of type 2 diabetes with good safety yet without occurrence of severe adverse effects, thus the therapy is worthy of clinical recommendation.