623例膀胱镜活检病理分析

Pathologic analysis of the cystoscopy in urinary bladder:a report of 623 cases

目的分析因膀胱病变行膀胱镜活检患者的病理类型构成,探讨膀胱镜检查的临床价值。方法复习我院623例膀胱病变患者经膀胱镜活检组织病理资料。结果良性肿瘤76例,占12.2%,均为尿路上皮乳头状瘤。恶性肿瘤291例,占46.7%,其中尿路上皮癌254例,腺癌17例,鳞癌6例,转移癌13例,横纹肌肉瘤1例。膀胱黏膜慢性炎症140例,上皮增生50例,分别占22.5%、8.0%;而腺性膀胱炎55例,正常膀胱黏膜8例,前列腺组织3例。结论尿路上皮性肿瘤仍是最常见的膀胱疾病,其次是膀胱炎性病变。膀胱恶性肿瘤以尿路上皮癌最常见,膀胱腺癌、鳞癌或转移癌等比较少见。膀胱镜活检安全、简便,具有重要的临床应用价值。

Objective To analyse the pathological feature of the bladder changes through cysto- scopic biopsy and discuss the clinical value of cystoscopy, Methods The bladder pathological tissues of 623 patients were reviewed. Results The 76 cases of benign tumors accounted for 12.2%, which were urothelial papilloma, while the 291 cases were malignant tumors, accounting for 46.7 ~. In these malignant tumors, 254 cases, 17 cases, 6 cases, 13 cases, 1 case were the urothelial carci- norna, adenocarcinoma, squamous carcinoma, metastatic carcinoma, rhabdomyosarcoma by cysto scopic biopsy, respectively. 140 cases were chronic cystitis accounted for 22.50/oo and 50 cases were epithelial hyperplasia accounted/＇or 8.0%, while 55 cases, 8 cases, 3 cases were the glandular cysti- tis, normal bladder mucosa and prostate tissue, respectively. Conclusions Urothelial tumor is still the most common bladder disease, followed by bladder inflammatory lesions. In bladder malig- nant tumor, the urothelial carcinoma is the most common, while bladder adenocarcinoma, squamous carcinoma or metastatic carcinoma is very rare. As a safe and simple diagnosis and treatment meth- od, cystoscopic biopsy has an important value of clinical application.