男性不育患者血浆抗精子抗体和精液抗精子抗体检测结果分析

Plasma antisperm antibodies and semen antisperm antibodies in male sterility patients detection results analysis

目的比较男性不育患者血浆AsAb和精液抗精子抗体(AsAb)的检测结果,对其在男性不育患者临床检测中的价值进行评价。方法运用酶联免疫吸附(ELISA)法对335例男性不育患者(已排除生殖道等器质性病变,且染色体正常)进行血浆抗精子抗体和精液抗精子抗体的检测。结果血浆抗精子抗体阳性78例,阳性率23.28%;精液抗精子抗体阳性32例,阳性率9.55%。运用SPSS10.5,进行χ2检验,P<0.05,差异有统计学意义。结论血浆AsAb检测的阳性率高于精液AsAb的阳性率。

Objective To compare the test results of plasma antisperm antibodies（AsAb） and semen antisperm antibodies（AsAb） in male sterility patients,and do value evaluation in clinical detection of the male sterility patients.Methods Detected plasma antisperm antibodies and semen antisperm antibodies in 335 male sterility patients（had excluded genital tract etc.organic lesions,and chromosome normal） by the method of enzyme-linked immunosorbent（ELISA）.Results There were 78 positive cases of the plasma antisperm antibodies,positive rate was 35.15%;and 26 positive cases of the semen antisperm antibodies,positive rate was 15.76%.Chi-square（χ2） inspection by SPSS10.5 was ased and got the result that P0.05 and there was significant difference.Conclusion Plasma antisperm antibodies（AsAb） detection positive rate is higher than the seminal plasma antisperm antibodies（AsAb） detection.