某地区乙型肝炎及丙型肝炎病毒感染调查分析

Investigation on hepatitis B and hepatitis C virus infection in a region

目的了解河北局部地区乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)感染情况,为预防和控制乙型肝炎、丙型肝炎病毒的感染提供科学依据。方法将该院检查人员按不同年龄分为3组:未成年组(0～<18岁),中青年组(18～60岁),老年组(60岁以上),并对3组的乙型肝炎和丙型肝炎病毒检测结果进行统计分析。采用酶联免疫吸附(ELISA)法进行乙型肝炎表面抗原(HBsAg)、丙型肝炎抗体(HCVAb)检测。结果乙型肝炎表面抗原(HBsAg)阳性率老年组(10.1%)、中青年组(14.1%)、未成年组(2.3%),组间比较差异有统计学意义(P<0.05);丙型肝炎抗体(HCVAb)阳性率老年组(1.8%)、中青年组(0.5%)、未成年组(0.3%),组间比较差异有统计学意义(P<0.05)。结论乙型肝炎表面抗原(HBsAg)阳性率呈下降趋势,广大群众应积极注射乙肝疫苗,定期检测,对乙肝疫苗无或低应答者及时进行乙肝疫苗的接种或加强,预防和阻断乙型肝炎病毒(HBV)的感染。加强丙型肝炎抗体(HCVAb)检测早发现早治疗。

Objective To investigate the infection situation of Hepatitis B virus and Hepatitis C Virus in the local area of Hebei province,for the prevention and control of hepatitis B（HBV） and hepatitis C virus（HCV） infection and providing the scientific basis.Methods The staff in our hospital according to different age were divided into three groups： the first group of minors（0-18 years old）,young people in the second group（18-60 years old）,and the third group of elderly people（aged over 60 years）.The detection results of hepatitis B and hepatitis C virus of the three groups were statistically analyzed.The enzyme-linked immunosorbent assay（ELISA） method was used for hepatitis B surface antigen（HBsAg） and hepatitis C antibody（HCVAb） detection.Results HBsAg among aged group（10.1%）,the young group（14.1%） and adult group（2.3%） was significantly different（P0.05）.The difference of HCVAb among aged group（1.8%）,the young group（0.5%） and minor group（0.3%） was statistically significant（P0.05）.Conclusion HBsAg positive rate shows a declining trend.The masses should regularly inject hepatitis B vaccine and check out.The people with no or low response to hepatitis B vaccine should to have or strengthen hepatitis B vaccination,in order to prevent and interdict HBV infection.The HCVAb detection should be strengthened,for early detection and treatment.