介入疗法治疗恶性胆道梗阻性黄疸42例

Interventional Therapy in the Treatment of 42 Patients with Malignant Obstructive Jaundice

目的探讨介入疗法对恶性胆道梗阻性黄疸的治疗效果。方法入组42例恶性胆道梗阻性黄疸患者,采用经皮肝穿刺胆管造影引流术(PTCD)和(或)裸金属内支架置入术,在胆道内置入内外引流管和(或)裸金属内支架,进行引流胆汁的姑息性治疗。结果全组42例患者经皮肝穿刺胆管术均一次成功,成功率100%。术后2周,血清总胆红素水平明显下降,肝功能明显改善。本组患者平均生存期为9个月,最长可达20个月。结论介入疗法对恶性胆道梗阻性黄疸是一种有效的姑息性治疗手段。

Objective To study the clinical efficacy of interventional therapy in the treatment of malignant obstructive jaundice. Methods Forty-two patients with malignant obstructive jaundice received the palliative therapy of bihary drainage through the drain pipe or uncovered metal stentt insertion by procedure of percutaneous transhepatic cholangiography and drainage （PTCD） or uncovered metal stent insertion. Results The successful rate of percutaneous transhepatic biliary drainage was 100%. In two weeks after treatment, the total serum bilirubin level decreased, and the liver function improved. The mean survival time of all the patients was 9 months, and the longest was 20 months. Conclusion Interventional therapy is effective for the patients with malignant obstructive jaundice.