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厄贝沙坦对高血压患者左室舒张功能的影响 被引量:3

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摘要 由于收缩期左室后负荷的增加.体内肾素血管紧张素醛固酮系统(Renin—angiotensin—system,RAS)被激活,释放相关激素促发心肌内新蛋白胶原基质的合成,引起心室重构,室壁顺应性减低,首先表现为以左室充盈受限为特点的左室舒张功能不全,可进展为左室肥厚。并进一步发展为左室射血分数保留的心力衰竭。
出处 《实用医药杂志》 2013年第7期588-589,共2页 Practical Journal of Medicine & Pharmacy
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