心血管疾病患者血脂水平与轻度认知功能障碍的相关性分析

Correlation between serum lipid levels and mild cognitive impairment in patients with cardiovascular diseases

目的探讨心血管疾病患者血脂水平与轻度认知功能障碍的相关性,为临床护理提供参考。方法将81例心血管疾病患者按血脂高低分为高血脂组(39例)和血脂正常组(42例)。采用简易精神状态量表(MMSE)对两组患者进行认知功能调查,并分析其与血脂水平的相关性。结果两组MMSE评分比较,差异无统计学意义(均P>0.05)。MMSE总分、回忆力、记忆力得分与高密度脂蛋白呈显著正相关(P<0.05,P<0.01)。结论高密度脂蛋白与记忆力和认知功能密切相关,对HDL水平偏低的患者实施针对性干预可望预防轻度认识功能障碍的发生或延缓发生时间。

Objective To explore the relationship between serum lipid levels and mild cognitive impairment in elderly patients with cardiovascular diseases,and to provide the basis for nursing care. Methods A total of 81 patients with cardiovascular diseases were divided into a hyperlipaemia group of 39 patients and a normal group of 42 patients according to their serum lipid levels. The two groups were investigated with the Mini-mental State Examination （MMSE）. And the relationship between scores of MMSE and serum lipid levels were analyzed. Results The scores of MMSE had no significant differences between the 2 groups（P〈0.05）. The total scores of MMSE, and the scores of the word recall dimension, were positively correlated with level of hyperdensity lipoprotein （HDL） （P〈0.05,P〈0.01）. Conclusion HDL was found to be closely related to memory and cognition function. If targeted nursing intervention is given to patients with low level of HDL,mild cognitive impairment may be prevented or delayed.