摘要
以乙交酯(GA)和两种不同旋光结构的丙交酯(LA)∶外消旋丙交酯(D,L-LA)和左旋丙交酯(L-LA)为原料,在聚乙二醇(PEG)引发下合成了一系列不同LA/GA摩尔比的聚乙二醇-聚丙交酯乙交酯(MPEG-PLGA)嵌段共聚物,并对其结构、结晶性、热性能和力学性能进行了分析测试。结果表明:由D,L-LA合成的共聚物均为非晶态,LA/GA的变化对其各方面性能影响较小;而L-LA合成的共聚物在LA/GA为75∶25时出现结晶性,90∶10时结晶度进一步增大,玻璃化转变温度及拉伸强度也随之明显提高。
By using glycolide（GA） and two different optical rotation lactide（LA）：D,I_lactide（D,LI.A） and Llac- tide（L-LA） ,a series of poly（ethylene glycol）-（lactide-co glycolide）（MPEG-PLGA） block copolymers with different LA/ GA molar ratios were prepared with methoxypolyethylene glycol（MPEG） as initiator. Their composition, crystallization, thermal and mechanical property were characterized and studied. Results showed that the copolymers synthesized by D, b LA were all amorphous, and the variation of LA/GA had little influence to their properties. The copolymers synthesized by 1A.A appeared crystallinity when LA/GA was 75 ： 25,the degree of crystallinity wasincreased when LA/GA was 90 ： 10, and their glass transition temperature and tensile strength was increased obviously with it.
出处
《化工新型材料》
CAS
CSCD
北大核心
2013年第7期88-90,共3页
New Chemical Materials
基金
国家“十二五”科技支撑计划课题(2012BAI31B06)
