脓毒症免疫抑制的机制及治疗的研究进展

Research progress in mechanism and treatment of sepsis with immunosuppression

脓毒症存在免疫抑制，其病理生理机制仍不明确，与炎症因子的失衡、免疫细胞数及功能改变有关。改善脓毒症免疫抑制成为治疗脓毒症新的方向，本文就近几年有关脓毒症免疫抑制的机制及治疗手段的研究状况做一综述。

Sepsis comes with immunosuppression. Although it has been known to correlate to the out - of - balance of inflammatory factors, the amount and function of immune cells, the pathophysiological mechanism of immunosuppression in sepsis is still not clear. Improvement of immunosuppression becomes a new direction for the treatment of sepsis. In this paper, the recent studies about the mechanism and treatment of sepsis with immunosuppression are reviewed.