济南市2012年托幼机构手足口病聚集性疫情流行病学分析

Epidemiological analysis of hand-foot-mouth disease clustering among Jinan kindergartens in 2012

目的了解济南市2012年托幼机构手足口病聚集性疫情的流行特征,为有效防控托幼机构手足口病聚集性疫情提供依据。方法应用描述性流行病学方法,对2012年济南市托幼机构手足口病聚集性病例流行特征、病原分布等资料进行分析。结果 2012年济南市共报告手足口病聚集疫情342起,其中托幼机构疫情214起(包括1起暴发疫情),累计病例734例。市区托幼机构聚集性病例发病率(15.61/10万)显著高于郊县(7.73/10万)(χ2=92.823,P<0.01)。4月托幼机构聚集病例开始上升,5—6月报告起数达到高峰。病例以3～4岁为主,占托幼机构聚集性疫情病例总数的81.20%。聚集性疫情主要以CoxA16病毒感染为主(56.77%)。结论托幼机构是手足口病聚集性疫情防控的重点场所,5—7月是防控工作的关键时期。

Objective To determine epidemiological features of Hand-Foot-Month Disease （HFMD） clustering among Jinan kindergartens in 2012, and to provide scientific basis for effective control of kindergarten HFMD clustering. Methods Epidemiologic characteristics and pathogen distribution of HFMD clustering among Jinan kindergartens in 2012 were analyzed. Results A total of 342 HFMD were reported in 2012, of which 214 happened in kindergartens （ including one outbreak ）, 734 cumulative cases were involved in kindergarten settings. Incidence of urban kindergarten was significantly higher than that in suburban ones （ 15.61/100 000 vs 7.73/100 000 ,X^2= 92. 823 ,P〈0.01）. Incidence rate began to rise during April during May to June. Most cases were aged 3-4 years （ 596 cases ） , which accounted for 81.20% of and then reached its / all kindergarten cases. peak The dominant pathogen was CoxA16, accounting for 56.77% of all positive cases. Conclusions Intervention and prevention measures should focus predominantly on kindergartens, especially during May to July.