摘要
目的 :探讨离子型造影剂和非离子型造影剂的毒副反应及其合理使用。方法 :随机抽取湖北医科大学附二医院CT室 1990～ 1996年作增强CT的病例 5 6 0 0例 ,比较离子型造影剂Angiografin和非离子型造影剂Ultravist的不良反应 ,全部病例采用团注非动态CT和动态CT。结果 :卡方检验结果可知两种造影剂不良反应发病率有明显差别 ,使用离子型造影剂者不良反应的发病率显著增高。结论 :从病人的生命安全角度出发应尽量采用非离子型造影剂 ,特别是高危因素的患者。
Objective:To discuss the adverse effects and rational use of ionic and nomonic contrast media.Methods:5 600 cases who had received contrast enhanced CT examination in our hospital from 1990 to 1996 were selected at random .Adverse reactions which resulted from ionic and nonionic contrast were compared retrospectively.CT enhanced examination was performed in bolus injection non dynamic and dynamic manner in all cases.Results:There is significan difference in adverse reactions between nonionic and ionic contrast through chi square test.Moreover,rates of adverse effects are significantly higher in ionic contrast than in nonionic one.Conclusion:Nonionic contrast ahould be suggested as much as posible for the sake of the patients' safety especially in high risk patients.
