小儿肾病综合征合并支气管哮喘临床分析

Clinical analysis of nephrotic syndrome with bronchial asthma

目的分析小儿肾病综合征(NS)与支气管哮喘之间的关系。方法医院2009年1月-2013年3月收治NS患儿228例,其中合并支气管哮喘症状12例,分析其诊断情况及NS与支气管哮喘的关系。结果 228例NS患儿合并支气管哮喘12例(5.3%),其中导致NS复发6例,2例NS患儿在NS未缓解期间,出现尿蛋白增多,服用激素治疗4周后,患儿尿蛋白尚未转阴。12例NS合并支气管哮喘患儿采用支气管扩张剂沙丁胺醇和表面激素布地奈德吸入治疗2～5d后,患儿哮喘症状得到缓解。12例患儿出院后,继续使用氟替卡松治疗,未再出现喘息,且对NS控制非常有效。结论对于NS合并支气管哮喘患儿,要有效控制患儿的哮喘症状,对患儿进行合理用药,能减少NS复发。

Objective To analyze the relationship between nephrotic syndrome （NS） and bronchial asthma. Methods The hospital admitted 228 cases children with NS in January 2009-March 2013, including 12 eases with bronchial asthma symp toms,analyzed its diagnostic and the relationship between NS and bronchial asthma. Results 228 cases children with NS in eluding 12 eases （5.3%） with bronchial asthma,which led to NS recurrence 6 eases,2 cases children with NS occurred urine protein increasing during NS without remission, after 4 weeks of taking hormone therapy, children with urinary protein had not been negative. 12 eases of NS with bronchial asthma were given bronehedilators salbutamol and budesonide inhalation surface hormone therapy for 2 ~ 5 d, asthma symptoms of children had been alleviated. After discharged, 12 eases eontinued using of flutieasone therapy, respite did not recur, and the NS control was very effective. Conclusion For children of NS with bronchial asthma,to control asthma svmotoms effectively.and give rational drug use.can reduce the recurrence of NS.