坦洛新联合山莨菪碱治疗输尿管下段结石临床观察

Clinical observation of tamsulosin combined with anisodamine in lower ureteral calculi

目的观察坦洛新联合山莨菪碱治疗输尿管下段结石的临床疗效。方法将60例结石直径<0.8cm的输尿管下段结石患者随机分为治疗组和对照组各30例。对照组给予左氧氟沙星治疗。治疗组在对照组基础上加用坦洛新联合山莨菪碱治疗。观察2组结石排出率及结石排出时间。结果治疗组结石排出率为76.7%高于对照组的36.7%,结石排出时间为(5±2)d短于对照组的(10±3)d,差异均有统计学意义(P<0.05)。结论坦洛新联合山莨菪碱治疗输尿管下段结石能显著提高结石排出率,缩短结石排出时间,值得临床推广应用。

Objective To observe the clinical efficacy of tamsulosin combined with anisodamine in lower ureteral cal culi. Methods 60 cases patients with lower ureteral calculi （ the diameter 〈 0. 8cm） were randomly divided into treatment group and control group,each of 30 cases. Control group was treated by levofloxacin,treatment group,on the basis of control group, was treated by tamsulosin combined with anisodamine. After treatment, compared the excretion rate and discharge time of calculi of 2 groups. Results The excretion rate of treatment group（76.7% ） was higher than that of control group（36.7% ）, the discharge time of treatment group [ （5 ＋ 2）d ] was shorter than that of control group [ （10± 3 ）d ], the difference was statis tically significant（ P 〈 0. 05 ）. Conclusion Tamsulosin combined with anisedamine in lower ureteral calculi can highly im prove the excretion rate of calculi, and shorten the discharge time of calculi.