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KLF2的研究进展 被引量：4

Research progress of KLF2
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摘要 肺Krtippel样转录因子（KLF2／LKLF）是锌指Krtippel样转录因子家族成员之一，由于最初发现KLF2主要在肺内表达因此也称为LKLF。研究表明KLF2在肺与血管的发育，T细胞静止、活化和迁移中起重要作用。近年的研究表明，KI。F2对许多疾病的发生、发展起重要作用，尤其对肺部炎性疾病起着至关重要的作用。本文就KLF2的结构和功能及其对疾病的影响作一综述。 Lung Kriappel-like transcription factor （KLF2 / LKLF） is a member of Krtippel-like zinc finger transcription factor family. Because it is initially found that KLF2 expresses in the lungs, it is also known as LKLF. The studies show that KLF2 plays an important role in the lung and vascular development, mature T cell survival, stationary, and migration. Recent studies suggest that KLF2 is involved in the occurrence and development of many diseases, especially plays a vital role in lung inflammatory diseases. This article reviews the structure and function of KLF2, and its impact on the disease.
作者 石丹丹 朱黎明 戴爱国
机构地区 南华大学附属省马王堆医院 湖南省老年医院呼吸疾病研究所
出处 《国际呼吸杂志》 2013年第14期1074-1077,共4页 International Journal of Respiration
关键词 肺Krtippel样转录因子 KLF2
分类号 R341 [医药卫生—基础医学]
  • 相关文献

参考文献33

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二级参考文献10

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共引文献3

同被引文献62

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引证文献4

二级引证文献6

国际呼吸杂志
2013年 第14期

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