长沙地区人群骨密度检测及骨质疏松症分析

Analysis of people's BMD and osteoporosis in Changsha area

目的通过872例长沙地区健康人群骨密度测定,为了解和研究长沙地区人群的骨密度(BMD)变化规律及骨质疏松症(Osteoporosis,OP)的发病状况,建立长沙地区骨密度正常参考值提供依据。方法用双能X线骨密度测量分析仪(DEXA)对长沙地区20-85岁的健康人群1331人BMD检测。男性624人,女性707人,按10岁一个年龄组进行统计分析。结果男性骨密度峰值在20-29岁,而女性骨密度峰值出现在30-39年龄段,然后随着年龄段的增高BMD逐渐下降,50岁以上女性和60岁以上男性的骨量呈迅速下降趋势(P<0.01);且骨质疏松发生率则女性显著高于男性(P<0.01)。结论骨质疏松发病率与年龄和性别具有一定的相关性。骨密度随年龄增长而下降,骨质疏松发病率随之增加,女性骨质疏松患病率高于男性。故女性骨质疏松的预防治疗应及早入手。

【Objective】To determine bone mineral density（BMD） of normal people in Changsha area and further to investigate the bone mineral density（BMD） changes and osteoporosis（Osteoporosis,OP） of the disease status.To establish of normal reference values and provide the basis for bone mineral density in Changsha area.【Methods】 BMD of lumber spine and proximal femur in 1 331（624 men,707 women） healthy people were determined by duel energy X-ray BMD detector（DEXA） in Changsha residents aged from 20 to 85 years old.All subjects were divided into different groups by 10 years for statistical analysis.【Results】The man peak bone mass was found between 20～ 29 years of age.But the female peak bone mass was found between 30 ～39 years of age.Female＇s bone mass decreased quickly after the age of 50.Man＇s bone mass decreased quickly after the age of 60（P〈0.01）.The incidence of osteoporosis in women was significantly higher than men（P〈0.01）.【Conclusions】The incidence of osteoporosis has some relevance with age and gender.BMD decreased with age,increased incidence of osteoporosis and female prevalence of osteoporosis in men.Therefore,prevention and treatment of osteoporosis in women should start as soon as possible.