摘要
目的研究查尔酮类化合物TPY的抗氧化、抗菌活性。方法测定TPY对DPPH.清除能力和总还原能力,测定TPY对大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌、沙门氏菌和变形杆菌等菌种的体外抑菌作用。结果 TPY的抗氧化能力呈现出明显的剂量依赖关系,具有良好的抗氧化活性。TPY对5种病菌具有不同程度的抑制作用。结论 TPY可作为一种理想的抗氧化和抑菌添加剂。
OBJECTIVE To study the antioxidant and antimicrobial activities of chalcone compound TPY.METHODS The antioxidant are evaluated in vitro by the capability of TPY for scavenging the DPPH free radical and reducing power.The antimicrobial activities are tested by using Escherichia coli,Staphylococcus aureus,Bacillus subtilis,Proteus and Salmonella.RESULTS The results showed that compound TPY has significant antioxidant activities,and dose dependent.In addition,compound TPY has more effective activity against the various bacillus.CONCLUSION The compound TPY is perfect additives as antioxidants and inhibiting microorganisms.
出处
《华西药学杂志》
CAS
CSCD
北大核心
2013年第4期343-345,共3页
West China Journal of Pharmaceutical Sciences
基金
浙江省自然科学基金项目(项目编号:LY12C19005)
关键词
查尔酮类
化合物TPY
抗氧化活性
抑菌活性
Chalcone compound
TPY
Antioxidant activities
Antimicrobial activities
